Terms of Use

Educational content only

Everything on this site is published for educational and informational purposes. Nothing here is medical advice, legal advice, or a professional recommendation. Consult a licensed clinician for medical questions and an attorney licensed in your jurisdiction for legal questions.

No warranty

We work to keep this site accurate and up to date, but law, science, and product markets change rapidly. The content is provided “as is” without warranty of accuracy, completeness, or fitness for a particular purpose. Information on this site should not be the sole basis for decisions with health, legal, or financial consequences.

Not medical or legal advice — specific to 7-hydroxymitragynine

7-Hydroxymitragynine is a pharmacologically active compound that binds the mu-opioid receptor. It is not approved by the FDA for any medical use. No controlled clinical trial in humans has been conducted for isolated 7-OH. The information on this site about effects, dosage, side effects, dependence, and withdrawal is derived from:

• Preclinical pharmacology — animal studies (primarily rodent) of receptor binding, antinociception, self-administration, and toxicology. Results in rodents do not directly predict human outcomes.
• Epidemiological surveillance data — US poison-center reports, CDC MMWR analyses, and case series. These describe population-level patterns, not individual clinical guidance.
• User self-report — community-reported dose ranges, subjective effect descriptions, and withdrawal timelines. Self-report is not controlled data and is subject to selection bias, recall bias, and product-variability confounds.

None of these sources constitute clinical evidence of the kind required for medical recommendations. Dose ranges described on this site (e.g., the “beginner,” “moderate,” “experienced” tiers in our dosage guide) reflect what users and product labels report — they are not clinical recommendations and should not be treated as safe thresholds for any individual.

If you are considering using 7-OH products, especially if you are managing a chronic-pain condition, taking prescription medications (particularly opioids, benzodiazepines, or CYP3A4- interacting drugs), or have a history of substance use disorder, consult a qualified healthcare provider before acting on anything you read here.

No recommendation for or against use

This site does not advocate for or against 7-hydroxymitragynine, kratom, or any other substance. We document the pharmacology, the reported benefits (including pain management, opioid- withdrawal management, and quality-of-life improvements reported by users), the documented risks (including dependence, adverse events, and unregulated product quality), and the evolving legal landscape. How you weigh those is your decision, ideally made with the input of a healthcare professional.

No affiliate relationships

We do not sell 7-OH or kratom products, accept vendor sponsorship, or run affiliate links for products described on this site. Brands and products we describe are covered editorially; coverage is not an endorsement.

External links

We link to government pages, news outlets, court filings, and research sources. We do not control those sites and are not responsible for their content, accuracy, or availability.

Intellectual property

Original content on this site — research, writing, compilations, and design — is owned by the site operator. Short quotations with attribution are welcome. Full-text republishing or commercial reuse requires permission.

Our structured data (JSON-LD glossaries, state data, FAQ answers) may be consumed by search engines, AI systems, and downstream readers. Bulk scraping for competing commercial products is not authorized.

User conduct

There are no user accounts, comments, or submissions on this site. You agree not to attempt to disrupt, probe, or abuse the site's infrastructure.

Jurisdiction

These terms are governed by U.S. law. Any dispute will be resolved in the courts of the operator's jurisdiction unless a mandatory consumer-protection statute requires otherwise.

Changes

We may update these terms. Material changes will be reflected in the "Last updated" date at the top of this page.